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Antihistamine Chlor-Trimeton

Written by Healthwords's team of doctors and pharmacists based in UK | Updated: 14.02.2023 | 2 min read

Chlor-trimeton (which contains chlorpheniramine) is an over-the-counter medicine known as a sedating antihistamine. It comes in tablet form. It is currently only available in a generic.

It is known as sedating as it can cause drowsiness side effects, and other antihistamines are non-drowsy such as loratadine. It is used to relieve the symptoms of allergies in a wide range of allergic conditions, including hay fever, insect bites, pet allergies, food allergies, contact dermatitis, and atopic eczema. Chlorpheniramine is useful in relieving symptoms of itching, sneezing, runny nose, skin rash, and red/itchy/watery eyes.

Who is it for?

This medication is used for anyone over the age of 2 years suffering from allergies caused by pollen (hay fever), animals, or food.

How does it work?

During an allergic reaction, your immune system releases a chemical called histamine, which is responsible for an allergy's symptoms. Antihistamines work by opposing the actions of histamine by stopping histamine binding to its target sites in the body.

The chemical structure of drowsy antihistamines means they can enter the brain through what is known as the blood-brain barrier. This makes them more likely to cause drowsiness compared to other antihistamines. Another antihistamine may be a better choice if you need to stay alert, such as for driving or performing skilled tasks.

Should anyone avoid taking it?

This medication should not be used by children under 2 years old unless instructed by your doctor. Like all medications, don’t take them if you have previously had an allergic reaction to the medication, if you have severe kidney or liver problems, or if you have other medications or medical conditions that you would normally discuss with your doctor or pharmacist before starting something new. Do not use it if you have breathing problems, glaucoma, or an enlarged prostate.

Are there any side-effects?

As with any medication, some people are bound to get unwanted side effects. Common symptoms include drowsiness, dry mouth, headaches, dizziness, blurred vision, and lack of concentration.

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